The Challenge of Non-Convulsive Seizures

Non-convulsive seizures, including cases of non-convulsive status epilepticus (NCSE), are common in critically ill patients in emergency departments and intensive care units.

of neurological ICU patients have seizures.1-21
of seizures in the ICU are non-convulsive and can only be detected by EEG.22
  • Non-convulsive seizures are difficult to detect and often go undiagnosed because patients exhibit little to no outward clinical signs
  • Prolonged non-convulsive seizures lead to permanent brain injury
  • Early detection and treatment of seizures is crucial for improving patient outcomes
"EEG should be initiated within 15-60 minutes of suspected Status Epilepticus in all patients.”
Guidelines for the Evaluation and Management of Status Epilepticus. Neurocritical Care. 2012 Aug;17(1):3-23.
4-60 hours to get
traditional EEG Results
EEG services often rely on a few key personnel, which makes emergency requests difficult - especially after hours. Without an EEG result, over-treatment can lead to increased sedation, prolonged length of stay, and unnecessary intubations while under-treatment can lead to prolonged seizures, increased length of hospital stay, and worse prognosis46.
Current EEG practice:
Complicated setup and workflow, with hours and days of delay

EEG is not widely available across hospitals, and where it is available, it suffers from long delays.

Recording and reading an EEG is complex and slow. The conventional EEG system is not designed for speed. It requires a specialized technician to connect electrodes to the scalp, set up the system, and record. Once the EEG data is collected, a trained EEG specialist is needed to interpret the recordings and relay the diagnostic information to physicians in the ICU and emergency department.